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Study: No Adverse Effects Between Lipitor, Grapefruit Juice

Lakeland Ledger – June 1, 2011

Florida Department of Citrus sponsored a 2003 clinical study headed by cardiologist Patrick Reddy of Watson Clinic on whether drinking grapefruit juice with Lipitor, the world’s top-selling cholesterol-­lowering drug, increases the drug’s effectiveness with no harmful side effects. Global grapefruit juice consumption has declined dramatically since the 1990s, when Lipitor came on the market, because of a rash of negative publicity about a potentially harmful drug interaction. Since then, Citrus Department officials have repeatedly turned down The Ledger’s request for the study’s results until publication in a medical journal. The British Journal of Clinical Pharmacology recently published the study’s findings, which show a small, clinically insignificant boost in Lipitor’s effectiveness but no adverse effects.

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